Matteo Jorgenson won the 2024 Dwars door Vlaanderen on Wednesday after his teammate Wout van Aert and Eritrea's Biniam Girmay were taken away in ambulances after a high-speed crash.

The 24-year-old Californian Jorgenson won the Paris-Nice earlier in March and confirmed his burgeoning status in his first season with Dutch team Visma.

Jorgenson broke away from an elite clique of six riders with a devastating turn of pace 6 kilometers away from the finish line after a 188-kilometer run with huge crowds.

"It's surreal," said Jorgenson, wiping tears from his eyes at the finish line.

Norway's Jonas Abrahamsen and the Swiss Stefan Kung was third, 29 seconds off the pace.

More memorably, a mass collision in the peloton caused by an uneven road surface felled up to a dozen unwitting riders, with Van Aert suffering major abrasions to his back, as his yellow Visma team jersey was ripped almost entirely off.

"I was on Wout's wheel when it happened," Jorgenson said. "It was a really ugly fall. We were going so fast. My thoughts are with Wout and all the guys involved. I have no news, all I know is he's in the hospital."

The accident occurred on a three-lane highway where there appeared to be one lane slightly higher than the neighboring two.

Other high-profile riders hurt were Belgian Jasper Stuyven of Lidl-Trek and his Danish teammate Mads Pedersen.

All four of those riders have won major classics and would have been contenders for the Tour of Flanders on Sunday and Paris-Roubaix the following Sunday, two major dates on the one-day racing calendar.

Van Aert was one of the favorites for Sunday's Tour of Flanders, where up to 750,000 fans usually turn out for Belgium's biggest sports event.

The 29-year-old Van Aert sobbed and rocked in agony as he was placed onto a stretcher and transferred to an ambulance.

Girmay's team Wanty confirmed the Eritrean 23-year-old "crashed hard during Dwars door Vlaanderen and is heading to hospital for checks."